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avatar for Diane Van Opstal

Diane Van Opstal

Erasmus Medical Center, Clinical Genetics
Laboratory Specialist Clinical Genetics
Rotterdam, Netherlands
Diane Van Opstal studied Biology at the University of Leuven (Belgium) and  after her study, since 1987, she has worked in the Prenatal Cytogenetics Laboratory of the Department of Clinical Genetics at the Erasmus Medical Centre in Rotterdam. She received her Ph.D. (“Molecular cytogenetics in prenatal diagnosis”) from the Erasmus University of Rotterdam (The Netherlands) in 1998. As a Laboratory Specialist Clinical Genetics, performing prenatal cytogenetic diagnostics and non-invasive genome-wide prenatal testing, she was involved in the development, validation and implementation in the laboratory of new techniques like FISH in the late eighties and later molecular techniques like MLPA, QF-PCR, aCGH and SNP arrays. She was also involved in the implementation of (extended) NIPT in the Netherlands. Her main research interests are the phenomenon of chromosomal mosaicism at the different stages of pregnancy, from conception up till birth, in preimplantation embryos, chorionic villi, amniotic fluid, fetus and placenta and the mechanisms of origin of chromosome aberrations. She also is a tutor of Laboratory Specialists Clinical Genetics since 2005.